Article
Genetic association studies of ACE and PAI-1 genes in women with recurrent pregnancy loss: a systematic review and meta-analysis.
Thrombosis and haemostasis - 1 Jan 2013
Su Mei-Tsz, Lin Sheng-Hsiang, Chen Yi-Chi, Kuo Pao-Lin
Abstract excerpt
A fine balance between coagulation and fibrinolysis is critical in early pregnancy. Plasminogen activator inhibitor-1 (PAI-1) and angiotensin converting enzyme (ACE) are involved in the fibrinolytic process, and several studies have reported the association between their gene polymorphisms and recurrent pregnancy loss (RPL). This study was conducted to investigate the association between PAI-1 and ACE...
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