Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diversity in the androgen receptor CAG repeat has been shaped by a multistep mutational mechanism.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Oct 2014

Santos Diana, Pimenta João, Wong Virginia C N, Amorim António, Martins Sandra

Abstract excerpt

The androgen receptor (AR) gene encodes a type of nuclear receptor that functions as a steroid-hormone activated transcription factor. In its coding region, AR includes a CAG repeat, which has been intensely studied due to the inverse correlation between repeat size and AR transcriptional activity. Several studies have reported different (CAG)n sizes associated with the risk of androgen-linked diseases. We aimed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asia
Share to Chromosomes, Human, X

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Europe

Share to Haplotypes

Share to Healthy Volunteers

Share to Linkage Disequilibrium

Share to Receptors, Androgen

Share to Trinucleotide Repeats

Source

Identifiers

PMID: 25078541
DOI: 10.1002/ajmg.b.32261

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diversity in the androgen receptor CAG repeat has been shaped by a multistep mutational mechanism.PMID 25078541Read ↗

CAG<i>n</i> Polymorphic Locus of Androgen Receptor (<i>AR</i>) Gene in Russian Infertile and Fertile MenSemantic proximity Read ↗

Role of the androgen receptor CAG repeat polymorphism in prostate cancer, and spinal and bulbar muscular atrophy.Semantic proximity Read ↗

Unexpected frequency of the pathogenic AR CAG repeat expansion in the general populationSemantic proximity Read ↗

Androgen Receptor Gene CAG Repeat Length Varies and Affects Semen Quality in an Ethnic-Specific Fashion in Young Men from RussiaSemantic proximity Read ↗

Wide range of reduced penetrance alleles in spinal and bulbar muscular atrophy: a model-based approach.Semantic proximity Read ↗

CAGn Polymorphic Locus of Androgen Receptor (AR) Gene in Russian Infertile and Fertile Men.Semantic proximity Read ↗

A Systematic Review of the Association between the Age of Onset of Spinal-Bulbar Muscular Atrophy (Kennedy’s Disease) and the Length of CAG Repeats in the Androgen Receptor GeneSemantic proximity Read ↗

Androgen insensitivity syndrome: do trinucleotide repeats in androgen receptor gene have any role?Semantic proximity Read ↗

The CAG repeat polymorphism within the androgen receptor gene and maleness<sup>1</sup>Semantic proximity Read ↗

The CAG repeat polymorphism of androgen receptor gene and prostate cancer: a meta-analysis.Semantic proximity Read ↗

Thirty-seven CAG repeats in the androgen receptor gene in two healthy individuals.Semantic proximity Read ↗

A large study of androgen receptor germline variants and their relation to sex hormone levels and prostate cancer risk. Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.