Article

A Systematic Review of the Association between the Age of Onset of Spinal-Bulbar Muscular Atrophy (Kennedy’s Disease) and the Length of CAG Repeats in the Androgen Receptor Gene

2023-02-09

Abstract excerpt

<h4>Background</h4> Spinal bulbar muscular atrophy (SBMA) is an X-linked recessive motor neuron disorder which is caused by the presence of ≥ 38 CAG repeats in the androgen receptor gene. Relatively little is known about SBMA, but existing literature indicates a relationship between CAG repeat number and the onset age of some motor symptoms of SBMA. This literature review explored the effect of larger CAG repeats...

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Literature Corpus work: 8f39bc2c-34ae-55ac-84af-6ba63e9a6b5f
DOI: 10.1101/2023.02.08.23285647

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