Article
Androgen insensitivity syndrome: do trinucleotide repeats in androgen receptor gene have any role?
Asian journal of andrology - 1 Jul 2008
Rajender Singh, Gupta Nalini J, Chakravarty Baidyanath, Singh Lalji, Thangaraj Kumarasamy
Abstract excerpt
AIM: To investigate the role of CAG and GGN repeats as genetic background affecting androgen insensitivity syndrome (AIS) phenotype. METHODS: We analyzed lengths of androgen receptor (AR)-CAG and GGN repeats in 69 AIS cases, along with 136 unrelated normal male individuals. The lengths of repeats were analyzed using polymerase chain reaction (PCR) amplification followed by allelic genotyping to determine allele...
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