Article
CAGn Polymorphic Locus of Androgen Receptor (AR) Gene in Russian Infertile and Fertile Men.
International journal of molecular sciences - 13 Nov 2024
Chernykh Vyacheslav, Solovova Olga, Sorokina Tatyana, Shtaut Maria, Sedova Anna, Bliznetz Elena, Ismagilova Olga, Beskorovainaya Tatiana, Shchagina Olga, Polyakov Aleksandr
Abstract excerpt
The androgen receptor (AR) is critical for mediating the effects of androgens. The polymorphic CAGn locus in exon 1 of the AR gene is associated with several diseases, including spinal and bulbar muscular atrophy (SBMA), prostate cancer, and male infertility. This study evaluated the CAGn locus in 9000 infertile Russian men and 286 fertile men (control group). The CAGn locus was analyzed using the amplified...
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