Article
Critical role of oncogenic KRAS in pancreatic cancer (Review).
Molecular medicine reports - 1 Jun 2016
Liu Jiang, Ji Shunrong, Liang Chen, Qin Yi, Jin Kaizhou, Liang Dingkon, Xu Wenyan, Shi Si, Zhang Bo, Liu Liang, Liu Chen, Xu Jin, Ni Quanxing, Yu Xianjun
Abstract excerpt
Pancreatic cancer is a human malignancy with one of the highest mortality rates and little progress has been achieved in its treatment in recent decades. Further improvement to the understanding of the biological and molecular mechanisms underlying the initiation and development of pancreatic ductal adenocarcinoma (PDAC) is required. Previous studies using genetically engineered mouse models have demonstrated...
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