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Article

Essential Role of Complement in Pregnancy: From Implantation to Parturition and Beyond

31 Jul 2020

Abstract excerpt

The complement cascade was identified over 100 years ago, yet investigation of its role in pregnancy remains an area of intense research. Complement inhibitors at the maternal-fetal interface prevent inappropriate complement activation to protect the fetus. However, this versatile proteolytic cascade also favorably influences numerous stages of pregnancy, including implantation, fetal development, and labor....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32849586
DOI: 10.3389/fimmu.2020.01681

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