Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The transcriptional landscape of cancer stem-like cell functionality in breast cancer.

Journal of translational medicine - 3 Jun 2024

Baldasici Oana, Soritau Olga, Roman Andrei, Lisencu Carmen, Visan Simona, Maja Laura, Pop Bogdan, Fetica Bogdan, Cismaru Andrei, Vlase Laurian, Balacescu Loredana, Balacescu Ovidiu, Russom Aman, Tudoran Oana

Abstract excerpt

BACKGROUND: Cancer stem-like cells (CSCs) have been extensively researched as the primary drivers of therapy resistance and tumor relapse in patients with breast cancer. However, due to lack of specific molecular markers, increased phenotypic plasticity and no clear clinicopathological features, the assessment of CSCs presence and functionality in solid tumors is challenging. While several potential markers, such...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Gene Expression Regulation, Neoplastic

Share to Neoplastic Stem Cells

Share to Spheroids, Cellular

Share to Transcription, Genetic

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 38831317
DOI: 10.1186/s12967-024-05281-w
PMCID: PMC11149333

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The transcriptional landscape of cancer stem-like cell functionality in breast cancer.PMID 38831317Read ↗

Identification of Breast Cancer Stem Cell Related Genes Using Functional Cellular Assays Combined With Single-Cell RNA Sequencing in MDA-MB-231 CellsSemantic proximity Read ↗

Breast cancer stem cells mediated CD8 <sup>+</sup> T cell exhaustion among different molecular subtypes of breast cancer regulated via NOTCH1/RBPJ/PD-L1 axisSemantic proximity Read ↗

Breast cancer stem cells: current advances and clinical implications.Semantic proximity Read ↗

Low-density lipoprotein receptor promotes crosstalk between cell stemness and tumor immune microenvironment in breast cancer: a large data-based multi-omics studySemantic proximity Read ↗

Breast cancer stem cells: an updateSemantic proximity Read ↗

Breast cancer stem cells: are we ready to go from bench to bedside?Semantic proximity Read ↗

Understanding breast cancer stem cell heterogeneity: time to move on to a new research paradigmSemantic proximity Read ↗

Cancer stem cells and their implication in breast cancer.Semantic proximity Read ↗

Stem Cells and Cellular Origins of Breast Cancer: Updates in the Rationale, Controversies, and Therapeutic ImplicationsSemantic proximity Read ↗

Cancer Stem Cell Transcriptome Landscape Reveals Biomarkers Driving Breast Cancer HeterogeneitySemantic proximity Read ↗

Concise Review: Breast Cancer Stem Cells: Regulatory Networks, Stem Cell Niches, and Disease RelevanceSemantic proximity Read ↗

Deciphering Common Traits of Breast and Ovarian Cancer Stem Cells and Possible Therapeutic ApproachesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.