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Article

APOBEC3F Properties and Hypermutation Preferences Indicate Activity against HIV-1 In Vivo

1 Aug 2004

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 15296757
DOI: 10.1016/j.cub.2004.06.050

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Related research

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APOBEC3F Properties and Hypermutation Preferences Indicate Activity against HIV-1 In VivoPMID 15296757Read ↗

APOBEC3G expression and hypermutation are inversely associated with human immunodeficiency virus type 1 (HIV-1) burden in vivoSemantic proximity Read ↗

Antiretroviral APOBEC3 Cytidine Deaminases Alter HIV-1 Provirus Integration Site ProfilesSemantic proximity Read ↗

Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation.Semantic proximity Read ↗

Leveraging APOBEC3 Proteins to Alter the HIV Mutation Rate and Combat AIDSSemantic proximity Read ↗

Conserved footprints of APOBEC3G on Hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequences.Semantic proximity Read ↗

Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3FSemantic proximity Read ↗

Turning up the volume on mutational pressure: Is more of a good thing always better? (A case study of HIV-1 Vif and APOBEC3)Semantic proximity Read ↗

APOBEC3G-induced hypermutation of human immunodeficiency virus type-1 is typically a discrete "all or nothing" phenomenon.Semantic proximity Read ↗

APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA.Semantic proximity Read ↗

The in vitro Biochemical Characterization of an HIV-1 Restriction Factor APOBEC3F: Importance of Loop 7 on Both CD1 and CD2 for DNA Binding and DeaminationSemantic proximity Read ↗

Variable contexts and levels of hypermutation in HIV-1 proviral genomes recovered from primary peripheral blood mononuclear cells.Semantic proximity Read ↗

Differential Activity of APOBEC3F, APOBEC3G, and APOBEC3H in the Restriction of HIV-2.Semantic proximity Read ↗

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