Article
In vitro immunomodulatory effects of microencapsulated umbilical cord Wharton jelly-derived mesenchymal stem cells in primary Sjögren's syndrome.
Rheumatology (Oxford, England) - 1 Jan 2015
Alunno Alessia, Montanucci Pia, Bistoni Onelia, Basta Giuseppe, Caterbi Sara, Pescara Teresa, Pennoni Ilaria, Bini Vittorio, Bartoloni Elena, Gerli Roberto, Calafiore Riccardo
Abstract excerpt
OBJECTIVE: Human umbilical cord Wharton jelly-derived mesenchymal stem cells (hUCMS) are easy to retrieve in bulk. They may interact with immune cells by either cell contact or soluble factors. Little evidence is currently available on potential therapeutic application of hUCMS to systemic autoimmune disorders such as primary SS (pSS). We have recently developed an endotoxin-free alginate gel that can be used to...
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