Article
Human umbilical cord mesenchymal stem cells alleviate ongoing autoimmune dacryoadenitis in rabbits via polarizing macrophages into an anti-inflammatory phenotype.
Experimental eye research - 1 Feb 2020
Lu Xiaoxiao, Li Na, Zhao Lu, Guo Di, Yi Huanfa, Yang Liyuan, Liu Xun, Sun Deming, Nian Hong, Wei Ruihua
Abstract excerpt
Mesenchymal stem cells (MSCs) exhibit beneficial effects on autoimmune dacryoadenitis. However, the underlying mechanisms are not fully understood. In this study, we investigated the therapeutic effect of human umbilical cord mesenchymal stem cells (hUC-MSCs) on rabbit autoimmune dacryoadenitis, an animal model of Sjögren's syndrome (SS) dry eye, and explored whether the effects of MSCs were related to their...
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