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Umbilical Mesenchymal Stem Cell-derived Exosomes Regulate CD4+ T cells in Patients with Primary Sjogren's Syndrome through the Autophagy Pathway

2022-07-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Primary Sjögren's syndrome (pSS) is an autoimmune disease that leads to the destruction of exocrine glands and formation of multisystem lesions. Abnormal proliferation, apoptosis, and differentiation of CD4<sup>+</sup> T cells are key factors in the pathogenesis of pSS, seriously affecting the appearance, progression, and outcome of the disease. Human umbilical...

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Literature Corpus work: 69e88c61-4943-5385-bbc4-244219524604
DOI: 10.21203/rs.3.rs-1843171/v1

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