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Article

Blood CSF1 and CXCL12 as Causal Mediators of Coronary Artery Disease.

Journal of the American College of Cardiology - 17 Jul 2018

Sjaarda Jennifer, Gerstein Hertzel, Chong Michael, Yusuf Salim, Meyre David, Anand Sonia S, Hess Sibylle, Paré Guillaume

Abstract excerpt

BACKGROUND: Identification of biomarkers that cause coronary artery disease (CAD) has led to important advances in prevention and treatment. Epidemiological analyses have identified many biomarker-CAD relationships; however, these associations may arise from reverse causation and/or confounding and therefore may not represent true causal associations. Mendelian randomization (MR) analyses overcome these...

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Source

Identifiers

PMID: 30012324
DOI: 10.1016/j.jacc.2018.04.067

Genes

CAD
CSF1
CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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