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Article

Genetic variation in melatonin pathway enzymes in children with autism spectrum disorder and comorbid sleep onset delay.

Journal of autism and developmental disorders - 1 Jan 2015

Veatch Olivia J, Pendergast Julie S, Allen Melissa J, Leu Roberta M, Johnson Carl Hirschie, Elsea Sarah H, Malow Beth A

Abstract excerpt

Sleep disruption is common in individuals with autism spectrum disorder (ASD). Genes whose products regulate endogenous melatonin modify sleep patterns and have been implicated in ASD. Genetic factors likely contribute to comorbid expression of sleep disorders in ASD. We studied a clinically unique ASD subgroup, consisting solely of children with comorbid expression of sleep onset delay. We evaluated variation in...

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Identifiers

PMID: 25059483
DOI: 10.1007/s10803-014-2197-4
PMCID: PMC4289108

Genes

ASMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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