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Article

Reference-free SNP detection: dealing with the data deluge.

BMC genomics - 1 Jan 2014

Leggett Richard M, MacLean Dan

Abstract excerpt

Reference-free SNP detection, that is identifying SNPs between samples directly from comparison of primary sequencing data with other primary sequencing data and not to a pre-assembled reference genome is an emergent and potentially disruptive technology that is beginning to open up new vistas in variant identification that reveals new applications in non-model organisms and metagenomics. The modern, efficient...

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PMID: 25056481
DOI: 10.1186/1471-2164-15-S4-S10
PMCID: PMC4083407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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