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Article

A portable recalibration workflow for reference-based variant calling in non-human genomes.

PLoS computational biology - 1 Aug 2026

Lee Hyeonjung, Kim Sunhee, Sunartha Michelle Audrelia, Lee Chang-Yong, Lee Young-Suk

Abstract excerpt

A key computational step in reference-based variant calling is distinguishing true genetic variants from sequencing errors. Advanced tools and workflows have been developed to handle this by computational modelling of technical errors from the sequencing machines. However, these recalibration workflows have largely been evaluated for human data only and its exact applicability for non-human data remains unknown....

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PMID: 42623377
DOI: 10.1371/journal.pcbi.1014603
PMCID: PMC13492802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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