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Article

Variable-order reference-free variant discovery with the Burrows-Wheeler Transform.

BMC bioinformatics - 16 Sept 2020

Prezza Nicola, Pisanti Nadia, Sciortino Marinella, Rosone Giovanna

Abstract excerpt

BACKGROUND: In [Prezza et al., AMB 2019], a new reference-free and alignment-free framework for the detection of SNPs was suggested and tested. The framework, based on the Burrows-Wheeler Transform (BWT), significantly improves sensitivity and precision of previous de Bruijn graphs based tools by overcoming several of their limitations, namely: (i) the need to establish a fixed value, usually small, for the order...

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PMID: 32938358
DOI: 10.1186/s12859-020-03586-3
PMCID: PMC7493873

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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