Article
High frequency and clinical prognostic value of MYD88 L265P mutation in primary cutaneous diffuse large B-cell lymphoma, leg-type.
JAMA dermatology - 1 Nov 2014
Pham-Ledard Anne, Beylot-Barry Marie, Barbe Coralie, Leduc Marion, Petrella Tony, Vergier Béatrice, Martinez Fabian, Cappellen David, Merlio Jean-Philippe, Grange Florent
Abstract excerpt
IMPORTANCE: The activating mutation of MYD88 L265P is a frequent feature of primary cutaneous diffuse large B-cell lymphoma, leg-type (PCLBCL-LT), reported in up to 69% of the cases. Whether patients with MYD88 mutation display specific clinical and evolutive features has not been evaluated. OBJECTIVE: To identify the clinical characteristics associated with MYD88 mutation, confirm its high prevalence, and...
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