MYD88 L265P Mutations, But No Other Variants, Identify a Subpopulation of DLBCL Patients of Activated B-cell Origin, Extranodal Involvement, and Poor Outcome.

doi:10.1158/1078-0432.CCR-15-1525

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Article

MYD88 L265P Mutations, But No Other Variants, Identify a Subpopulation of DLBCL Patients of Activated B-cell Origin, Extranodal Involvement, and Poor Outcome.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2016

Rovira Jordina, Karube Kennosuke, Valera Alexandra, Colomer Dolors, Enjuanes Anna, Colomo Lluís, Martínez-Trillos Alejandra, Giné Eva, Dlouhy Ivan, Magnano Laura, Delgado Julio, Martínez Antonio, Villamor Neus, Campo Elías, López-Guillermo Armando

Abstract excerpt

PURPOSE: Mutations in MYD88 are found in different lymphoproliferative disorders associated with particular biologic characteristics and clinical impact. The aim of this study was to analyze the incidence of MYD88 mutations and its clinical impact in diffuse large B-cell lymphoma (DLBCL). EXPERIMENTAL DESIGN: The incidence, clinicobiological features, and outcome of 213 patients (115 M/98 F; median age, 65 years)...

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PMID: 26792260
DOI: 10.1158/1078-0432.CCR-15-1525

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MYD88

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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