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Article

Mutations in mmpL and in the cell wall stress stimulon contribute to resistance to oxadiazole antibiotics in methicillin-resistant Staphylococcus aureus.

Antimicrobial agents and chemotherapy - 1 Oct 2014

Xiao Qiaobin, Vakulenko Sergei, Chang Mayland, Mobashery Shahriar

Abstract excerpt

Staphylococcus aureus is a leading cause of hospital- and community-acquired infections, which exhibit broad resistance to various antibiotics. We recently disclosed the discovery of the oxadiazole class of antibiotics, which has in vitro and in vivo activities against methicillin-resistant S. aureus (MRSA). We report herein that MmpL, a putative member of the resistance, nodulation, and cell division (RND)...

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Identifiers

PMID: 25049248
DOI: 10.1128/AAC.03501-14
PMCID: PMC4187926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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