Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synergistic association between two alcohol metabolism relevant genes and coronary artery disease among Chinese hypertensive patients.

PloS one - 1 Jan 2014

Wang Yuefei, Du Fengxia, Zhao Hongye, Yu Xiaohong, Liu Jun, Xiao Yu, Lu Changzhu, Li Xue, Wang Yanli, Wang Bin, Niu Wenquan

Abstract excerpt

OBJECTIVE: Coronary artery disease (CAD) is a multifactorial and polygenic disease. The aim of this study was to examine the association between six polymorphisms of four alcohol metabolism relevant genes (ADH1B, ADH1C, ALDH1b1, ALDH2) and the risk of CAD in Han Chinese. METHODS AND RESULTS: This was a hospital-based case-control study involving 1365 hypertensive patients. All study subjects were angiographically...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aldehyde Dehydrogenase
Share to Aldehyde Dehydrogenase 1 Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aldehyde Dehydrogenase, Mitochondrial

Share to Asian People

Share to Coronary Artery Disease

Share to Haplotypes

Share to Hypertension

Source

Open in PubMed Open full text

Identifiers

PMID: 25047496
DOI: 10.1371/journal.pone.0103161
PMCID: PMC4105442

Genes

CAD
ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Synergistic association between two alcohol metabolism relevant genes and coronary artery disease among Chinese hypertensive patients.PMID 25047496Read ↗

Association of genetic polymorphisms in ADH and ALDH2 with risk of coronary artery disease and myocardial infarction: a meta-analysis.Semantic proximity Read ↗

Aldehyde dehydrogenase 2 (ALDH2) polymorphism gene and coronary artery disease risk: a meta-analysis.Semantic proximity Read ↗

ALDH2 gene G487A polymorphism and coronary artery disease: a meta-analysis including 5644 participants.Semantic proximity Read ↗

ALDH2, ADCY3 and BCMO1 polymorphisms and lifestyle-induced traits are jointly associated with CAD risk in Chinese Han people.Semantic proximity Read ↗

The Glu504Lys polymorphism of aldehyde dehydrogenase 2 contributes to development of coronary artery disease.Semantic proximity Read ↗

Impact of interaction between CYP1A1 genetic polymorphisms and smoking on coronary artery disease in the Han of China.Semantic proximity Read ↗

Interactions between ALDH2 rs671 polymorphism and lifestyle behaviors on coronary artery disease risk in a Chinese Han population with dyslipidemia: A guide to targeted heart health management.Semantic proximity Read ↗

Gene-gene interaction between PPARG and CYP1A1 gene on coronary artery disease in the Chinese Han Population.Semantic proximity Read ↗

ALDH2 rs671 Polymorphism and coronary heart disease risk among Asian populations: a meta-analysis and meta-regression.Semantic proximity Read ↗

Aldehyde dehydrogenase 2-associated metabolic abnormalities and cardiovascular diseases: current status, underlying mechanisms, and clinical recommendationsSemantic proximity Read ↗

Synergistic association of DNA repair relevant gene polymorphisms with the risk of coronary artery disease in northeastern Han Chinese.Semantic proximity Read ↗

Associations of common variants at ALDH2 gene and the risk of stroke in patients with coronary artery diseases undergoing percutaneous coronary intervention.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.