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Article

Synergistic association of DNA repair relevant gene polymorphisms with the risk of coronary artery disease in northeastern Han Chinese.

Thrombosis research - 1 Feb 2014

Yu Xiaohong, Liu Jun, Zhu Hao, Xia Yunlong, Gao Lianjun, Dong Yingxue, Jia Nan, Shen Weifeng, Yang Yanzong, Niu Wenquan

Abstract excerpt

Evidence is mounting suggesting that DNA damage is implicated in the development and progression of atherosclerosis. To yield more information, we focused on six well-characterized polymorphisms from four DNA repair-relevant candidate genes, viz. XRCC1 (rs1799782 and rs25487), XRCC3 (rs861539), MTHFR (rs1801133 and rs4846049), and NQO1 (), to identify and characterize their potential gene-to-gene...

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Source

Identifiers

PMID: 24315498
DOI: 10.1016/j.thromres.2013.11.017

Genes

CAD
MTHFR
XRCC1
NQO1
XRCC3

Provenance

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