Article
ALDH2 rs671 Polymorphism and coronary heart disease risk among Asian populations: a meta-analysis and meta-regression.
DNA and cell biology - 1 Jul 2013
Wang Qi, Zhou Shaobo, Wang Lijie, Lei Mingming, Wang Yong, Miao Chi, Jin Yuanzhe
Abstract excerpt
Mitochondrial aldehyde dehydrogenase-2 (ALDH2) is the principal enzyme involved in alcohol metabolism in humans. Emerging evidence has shown that the common rs671 G>A (Glu504Lys) polymorphism in the ALDH2 gene might play a critical role in increasing the susceptibility to coronary heart disease (CHD), including myocardial infarction (MI); however, individually published studies showed inconclusive results. This...
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