Article
Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell-like property of hepatocellular carcinoma cells by stabilizing NOP2.
Hepatology (Baltimore, Md.) - 1 Oct 2014
Wang Fang, Yuan Ji-Hang, Wang Shao-Bing, Yang Fu, Yuan Sheng-Xian, Ye Chen, Yang Ning, Zhou Wei-Ping, Li Wen-Lin, Li Wen, Sun Shu-Han
Abstract excerpt
UNLABELLED: Many protein-coding oncofetal genes are highly expressed in murine and human fetal liver and silenced in adult liver. The protein products of these hepatic oncofetal genes have been used as clinical markers for the recurrence of hepatocellular carcinoma (HCC) and as therapeutic targets for HCC. Herein we examined the expression profiles of long noncoding RNAs (lncRNAs) found in fetal and adult liver...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
