Article
Transiently truncated and differentially regulated expression of midkine during mouse embryogenesis.
Biochemical and biophysical research communications - 20 May 2005
Chen Qin, Yuan Yuanyang, Lin Shuibin, Chang Youde, Zhuo Xinming, Wei Wei, Tao Ping, Ruan Lingjuan, Li Qifu, Li Zhixing
Abstract excerpt
Midkine (MK) is a retinoic acid response cytokine, mostly expressed in embryonic tissues. Aberrant expression of MK was found in numerous cancers. In human, a truncated MK was expressed specifically in tumor/cancer tissues. Here we report the discovery of a novel truncated form of MK transiently expressed during normal mouse embryonic development. In addition, MK is concentrated at the interface between...
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