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Article

The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD transcription-competent complex.

Genome biology - 20 Dec 2017

Verduci Lorena, Ferraiuolo Maria, Sacconi Andrea, Ganci Federica, Vitale Jlenia, Colombo Teresa, Paci Paola, Strano Sabrina, Macino Giuseppe, Rajewsky Nikolaus, Blandino Giovanni

Abstract excerpt

BACKGROUND: Circular RNAs are a class of endogenous RNAs with various functions in eukaryotic cells. Worthy of note, circular RNAs play a critical role in cancer. Currently, nothing is known about their role in head and neck squamous cell carcinoma (HNSCC). The identification of circular RNAs in HNSCC might become useful for diagnostic and therapeutic strategies in HNSCC. RESULTS: Using samples from 115 HNSCC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29262850
DOI: 10.1186/s13059-017-1368-y
PMCID: PMC5738800

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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