Article
Comparison of loading with maintenance dose of clopidogrel on platelet reactivity in Chinese with different CYP2C19 genotypes prior to percutaneous coronary intervention.
Chinese medical journal - 1 Jan 2014
Zhang Xiaoxing, Yan Lirong, Wang Dongxue, Li Yan, Han Lulu, Tian Lei, Liu Hong, Li Yishi
Abstract excerpt
BACKGROUND: Whether two clopidogrel pretreatment strategies prior to elective percutaneous coronary intervention (PCI): a 300 mg loading dose (LD) in clopidogrel naїve patients and a 75 mg maintenance dose (MD) once daily in patients on chronic clopidogrel therapy play the same role in the platelet inhibition in Chinese with different CYP2C19 genotypes remains unknown. We aim to evaluate the impact on platelet...
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