Article
Epstein-Barr virus infection induces an increase of T regulatory type 1 cells in Hodgkin lymphoma patients.
British journal of haematology - 1 Sept 2014
Morales Olivier, Mrizak Dhafer, François Violaine, Mustapha Rami, Miroux Céline, Depil Stéphane, Decouvelaere Anne-Valérie, Lionne-Huyghe Pauline, Auriault Claude, de Launoit Yvan, Pancré Véronique, Delhem Nadira
Abstract excerpt
Epstein-Barr Virus (EBV) is present in the neoplastic cells of around 20-30% of patients with Hodgkin Lymphoma (HL). Although, an immunosuppressive environment is currently described in HL patients, little is known concerning the regulatory mechanism induced by EBV proteins expression in tumour cells. This study aimed to investigate an association between regulatory Type 1 cells (Tr1) and EBV tissue positivity in...
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