Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Profiling of immune related genes silenced in EBV-positive gastric carcinoma identified novel restriction factors of human gammaherpesviruses

25 Aug 2020

Abstract excerpt

EBV-associated gastric cancer (EBVaGC) is characterized by high frequency of DNA methylation.In this study, we investigated how epigenetic alteration of host genome contributes to pathogenesis of EBVaGC through the analysis of transcriptomic and epigenomic datasets from NIH TCGA (The Cancer Genome Atlas) consortium.We identified that immune related genes (IRGs) is a group of host genes preferentially silenced in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to RNA modifications and cancer
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32841292
DOI: 10.1371/journal.ppat.1008778

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Profiling of immune related genes silenced in EBV-positive gastric carcinoma identified novel restriction factors of human gammaherpesvirusesPMID 32841292Read ↗

Genome‐wide identification of Epstein‐Barr virus–driven promoter methylation profiles of human genes in gastric cancer cellsSemantic proximity Read ↗

Tumor-Infiltrating T Cells in EBV-Associated Gastric Carcinomas Exhibit High Levels of Multiple Markers of Activation, Effector Gene Expression, and ExhaustionSemantic proximity Read ↗

The oncogenic role of Epstein–Barr virus‐encoded micro RNA s in Epstein–Barr virus‐associated gastric carcinomaSemantic proximity Read ↗

Unmasking Epstein-Barr Role in Gastric Carcinogenesis: A Gene Expression Approach to Virus-Positive TumorsSemantic proximity Read ↗

Differences in the Tumor Microenvironment of EBV-Associated Gastric Cancers Revealed Using Single-Cell Transcriptome AnalysisSemantic proximity Read ↗

Epigenetic dysregulation in Epstein-Barr virus-associated gastric carcinoma: Disease and treatmentsSemantic proximity Read ↗

Regulation of tumour related genes by dynamic epigenetic alteration at enhancer regions in gastric epithelial cells infected by Epstein-Barr virusSemantic proximity Read ↗

Epstein-Barr Virus-Associated Gastric Carcinoma: Use of Host Cell Machineries and Somatic Gene Mutations.Semantic proximity Read ↗

Epstein-Barr virus-positive gastric cancer: a distinct molecular subtype of the disease?Semantic proximity Read ↗

The Role of Epigenetic Regulation in Epstein-Barr Virus-Associated Gastric CancerSemantic proximity Read ↗

Epstein–Barr Virus and gastric carcinoma pathogenesis with emphasis on underlying epigenetic mechanismsSemantic proximity Read ↗

PD-L1 overexpression in EBV-positive gastric cancer is caused by unique genomic or epigenomic mechanismsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.