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Article

The design and methods of genetic studies on acute and chronic postoperative pain in patients after total knee replacement.

Pain medicine (Malden, Mass.) - 1 Sept 2014

Belfer Inna, Greco Carol M, Lokshin Anna, Vulakovich Katie, Landsittel Douglas, Dai Feng, Crossett Lawrence, Chelly Jacques E

Abstract excerpt

OBJECTIVE: Total knee replacement (TKR) is the treatment option of choice for the millions of individuals whose osteoarthritis pain can no longer be managed through non-invasive methods. Over 500,000 TKRs are performed annually in the United States. Although most patients report improvement in pain and functioning following TKR, up to 30% report persistent pain that interferes with daily function. However, the...

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Identifiers

PMID: 25040948
DOI: 10.1111/pme.12487
PMCID: PMC4556363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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