Article
Single-step SNP-BLUP with on-the-fly imputed genotypes and residual polygenic effects.
Genetics, selection, evolution : GSE - 30 Mar 2017
Taskinen Matti, Mäntysaari Esa A, Strandén Ismo
Abstract excerpt
BACKGROUND: Single-step genomic best linear unbiased prediction (BLUP) evaluation combines relationship information from pedigree and genomic marker data. The inclusion of the genomic information into mixed model equations requires the inverse of the combined relationship matrix [Formula: see text], which has a dense matrix block for genotyped animals. METHODS: To avoid inversion of dense matrices, single-step...
Topics
- Algorithms
- Animals
- Genome-Wide Association Study
- Genotype
- Multifactorial Inheritance
- Polymorphism, Single Nucleotide