Article
Preparation of triple-negative breast cancer vaccine through electrofusion with day-3 dendritic cells.
PloS one - 1 Jan 2014
Zhang Peng, Yi Shuhong, Li Xi, Liu Ruilei, Jiang Hua, Huang Zenan, Liu Yu, Wu Juekun, Huang Yong
Abstract excerpt
Dendritic cells (DCs) are professional antigen-presenting cells (APCs) in human immune system. DC-based tumor vaccine has met with some success in specific malignancies, inclusive of breast cancer. In this study, we electrofused MDA-MB-231 breast cancer cell line with day-3 DCs derived from peripheral blood monocytes, and explored the biological characteristics of fusion vaccine and its anti-tumor effects in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
