Article
Predominant role of GIP in the development of a metabolic syndrome-like phenotype in female Wistar rats submitted to forced catch-up growth.
Endocrinology - 1 Oct 2014
De Toro-Martín J, Fernández-Millán E, Lizárraga-Mollinedo E, López-Oliva E, Serradas P, Escrivá F, Alvarez C
Abstract excerpt
Catch-up growth has been associated with the appearance of metabolic dysfunctions such as obesity and type 2 diabetes in adulthood. Because the entero-insular axis is critical to glucose homeostasis control, we explored the relevance of the incretins glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) in the development of these pathologies. Offspring of rat dams fed ad libitum...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
