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Article

Nerve growth factor in diabetic retinopathy: beyond neurons

22 Mar 2014

Abstract excerpt

Diabetic retinopathy (DR), a major ocular complication of diabetes, is a leading cause of blindness in US working age adults with limited treatments. Neurotrophins (NTs), a family of proteins essential for growth, differentiation and survival of retinal neurons, have emerged as potential players in the pathogenesis of DR. NTs can signal through their corresponding tropomyosin kinase related receptor to mediate...

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PMID: 25031607
DOI: 10.1586/17469899.2014.903157

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