Article
Genome-wide association study of hepatitis C virus- and cryoglobulin-related vasculitis.
Genes and immunity - 1 Oct 2014
Zignego A L, Wojcik G L, Cacoub P, Visentini M, Casato M, Mangia A, Latanich R, Charles E D, Gragnani L, Terrier B, Piazzola V, Dustin L B, Khakoo S I, Busch M P, Lauer G M, Kim A Y, Alric L, Thomas D L, Duggal P
Abstract excerpt
The host genetic basis of mixed cryoglobulin vasculitis is not well understood and has not been studied in large cohorts. A genome-wide association study was conducted among 356 hepatitis C virus (HCV) RNA-positive individuals with cryoglobulin-related vasculitis and 447 ethnically matched, HCV RNA-positive controls. All cases had both serum cryoglobulins and a vasculitis syndrome. A total of 899 641 markers from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.