Article
Pharmacogenetic analysis of hepatitis C virus related mixed cryoglobulinemia.
Pharmacogenomics - 1 May 2017
Cusato Jessica, Boglione Lucio, De Nicolò Amedeo, Cardellino Chiara Simona, Carcieri Chiara, Cariti Giuseppe, Di Perri Giovanni, D'Avolio Antonio
Abstract excerpt
AIM: Mixed cryoglobulinemia (MC) is an extra hepatic hepatitis C virus related problem and different studies suggested genetics' role in predicting this complication. We evaluated the influence of SNPs in IL-28B, SLC29A1, SLC28A2, NT5C2, HNF4 and ABCB1 genes in MC prediction. PATIENTS & METHODS: SNPs were evaluated through real-time PCR. RESULTS: ABCB1 (gene encoding P-glycoprotein) 3435C>T SNP was associated...
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