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Article

A copper-responsive gene cluster is required for copper homeostasis and contributes to oxidative resistance in Deinococcus radiodurans R1.

Molecular bioSystems - 1 Oct 2014

Zhao Zhongchao, Zhou Zhengfu, Li Liang, Xian Xianyi, Ke Xiubin, Chen Ming, Zhang Yuxiu

Abstract excerpt

Excess copper is toxic to organisms, and therefore, copper homeostasis is important for the limitation of its cellular levels. However, copper homeostasis has not been studied to date in the bacteria Deinococcus radiodurans R1, which exhibits extreme resistance to various environmental stresses. We have identified a copper-responsive gene cluster that encodes CopA, which is a copper-transporting P1-type ATPase,...

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PMID: 25030084
DOI: 10.1039/c4mb00320a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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