Article
Investigation of the association between obesity and insulin-induced gene 1 polymorphism at 7q36.3 region in Uygur population in Xinjiang, China.
Bioscience reports - 20 Dec 2019
Tao Jing, Abudoukelimu Mayila, Shen Xin, Liu Jun, Wang Feng-Xia, Yuan Jie, Gu Pei-Pei, Zhu Wei, Zhang Xiao-Tian, Wang Zhao, Ma Yi-Tong, Li Guo-Qing
Abstract excerpt
BACKGROUND: Obesity is a common heritable trait and a major risk factors of chronic and metabolic diseases. Insulin-induced gene 1 (INSIG1) is known to play important roles in cholesterol and triacylglycerol (TAG) metabolism. In the present study, our primary objective was to explore whether the single nucleotide polymorphisms (SNPs) in INSIG1 gene were associated with obesity in Uygur subjects, in Xinjiang,...
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