Article
LRRK2 G2385R variant carriers of female Parkinson's disease are more susceptible to motor fluctuation.
Journal of neurology - 1 Nov 2013
Gao Chao, Pang Hao, Luo Xiao-Guang, Ren Yan, Shang Hong, He Zhi-Yi
Abstract excerpt
The relation between the LRRK2 mutation and its effect on Parkinson's disease (PD) has always caught a lot attention. Recent studies found that the G2385R polymorphism of LRRK2 may increase the risk of PD in Asian populations. Here we tried to clarify the relationship between the LRRK2 G2385R variant and the clinical profiles including motor complication in Chinese PD patients. We identified the LRRK2 variant in...
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