Article
Clinical significance of phenotyping and karyotyping of circulating tumor cells in patients with advanced gastric cancer.
Oncotarget - 30 Aug 2014
Li Yilin, Zhang Xiaotian, Ge Sai, Gao Jing, Gong Jifang, Lu Ming, Zhang Qiyue, Cao Yanshuo, Wang Daisy Dandan, Lin Peter Ping, Shen Lin
Abstract excerpt
BACKGROUND: Karyotyping and phenotyping of circulating tumor cells (CTCs) in therapeutic cancer patients is of particular clinical significance in terms of both identifying chemo-resistant CTC subtypes and understanding CTC evolution. METHODS: The integrated subtraction enrichment (SET) and immunostaining-fluorescence in situ hybridization (iFISH) platform was applied to detect and characterize CTCs in patients...
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