Genetic Variants Within Key Nodes of the Cascade of Antipsychotic Mechanisms: Effects on Antipsychotic Response and Schizophrenia Psychopathology in a Naturalistic Treatment Setting in Two Independent Korean and Italian Samples.

doi:10.1007/s12325-017-0555-2

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Genetic Variants Within Key Nodes of the Cascade of Antipsychotic Mechanisms: Effects on Antipsychotic Response and Schizophrenia Psychopathology in a Naturalistic Treatment Setting in Two Independent Korean and Italian Samples.

Advances in therapy - 1 Jun 2017

Calabrò Marco, Porcelli Stefano, Crisafulli Concetta, Wang Sheng-Min, Lee Soo-Jung, Han Changsu, Patkar Ashwin A, Masand Prakash S, Albani Diego, Raimondi Ilaria, Forloni Gianluigi, Bin Sofia, Mattiaccio Alessandro, Mantovani Vilma, Jun Tae-Youn, Pae Chi-Un, Serretti Alessandro

Abstract excerpt

INTRODUCTION: Schizophrenia (SCZ) is one of the most disabling psychiatric disorders. Genetic factors play an important role in both SCZ liability and its treatment outcome. In the present paper, we investigated the effects of several single nucleotide polymorphisms (SNPs) within ten strong candidate genes involved with antipsychotics (APs) mechanisms of action. METHODS: Two independent samples were investigated...

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PMID: 28508933
DOI: 10.1007/s12325-017-0555-2

Genes

ESYT2
NCAPG2
HOMER1
PKDCC
ARC
BDNF
TXNRD2

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