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Article

Association analysis of GABRB3 promoter variants with heroin dependence.

PloS one - 1 Jan 2014

Chen Chia-Hsiang, Huang Chia-Chun, Liao Ding-Lieh

Abstract excerpt

GABRB3 encoding the β3 subunit of GABAA receptor has been implicated in multiple neuropsychiatric disorders, including substance abuse. Previous studies reported that SNPs at the 5' regulatory region of GABRB3 could regulate GABRB3 gene expression and associated with childhood absence epilepsy (CAE). The study aimed to investigate whether SNPs at the 5' regulatory region of GABRB3 were associated with heroin...

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Topics

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Share to Promoter Regions, Genetic
Share to GABRB3 gene
Share to Heroin Dependence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Receptors, GABA-A

Source

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Identifiers

PMID: 25025424
DOI: 10.1371/journal.pone.0102227
PMCID: PMC4098998

Genes

GABRB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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