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Article

Polymorphisms in the glutamate decarboxylase 1 gene associated with heroin dependence.

Biochemical and biophysical research communications - 25 May 2012

Wu W, Zhu Y S, Li S B

Abstract excerpt

The GAD1 gene encodes the 67-kDa glutamic acid decarboxylase isoform (GAD67), the rate-limiting enzyme responsible for γ-aminobutyric acid (GABA) biosynthesis from glutamic acid, and may be involved in the development of drug dependence. To identify markers contributing to the genetic susceptibility to heroin dependence, this study examined the potential association between heroin dependence and 15 single...

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Source

Identifiers

PMID: 22564729
DOI: 10.1016/j.bbrc.2012.04.112

Genes

GAD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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