Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Type II Toxoplasma gondii Induction of CD40 on Infected Macrophages Enhances Interleukin-12 Responses

15 Jul 2014

Abstract excerpt

Toxoplasma gondii is an obligate intracellular parasite that can cause severe neurological disease in infected humans. CD40 is a receptor on macrophages that plays a critical role in controlling T. gondii infection. We examined the regulation of CD40 on the surface of T. gondii-infected bone marrow-derived macrophages (BMdMs). T. gondii induced CD40 expression both at the transcript level and on the cell surface,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Toxoplasma gondii Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25024369
DOI: 10.1128/iai.01615-14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Type II Toxoplasma gondii Induction of CD40 on Infected Macrophages Enhances Interleukin-12 ResponsesPMID 25024369Read ↗

<i>Toxoplasma</i> type II effector GRA15 has limited influence <i>in vivo</i>Semantic proximity Read ↗

Strain-specific activation of the NF-κB pathway by GRA15, a novel <i>Toxoplasma gondii</i> dense granule proteinSemantic proximity Read ↗

Toxoplasma GRA15 Activates the NF-κB Pathway through Interactions with TNF Receptor-Associated FactorsSemantic proximity Read ↗

Hypermigration of macrophages through the concerted action of GRA effectors on NF-κB/p38 signaling and host chromatin accessibility potentiates <i>Toxoplasma</i> disseminationSemantic proximity Read ↗

Hypermigration of macrophages through the concerted action of GRA effectors on NF-κB/p38 signaling and host chromatin accessibility potentiates Toxoplasma disseminationSemantic proximity Read ↗

The <i> ROP16 <sub>III</sub> </i> -dependent early immune response determines the sub-acute CNS immune response and type III <i>Toxoplasma gondii</i> survivalSemantic proximity Read ↗

Toxoplasma gondii effector TgIST blocks type I interferon signaling to promote infectionSemantic proximity Read ↗

Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against Toxoplasma gondiiSemantic proximity Read ↗

Early immune response to Toxoplasma gondii lineage III isolates of different virulence phenotype.Semantic proximity Read ↗

Production of IL-12 by macrophages infected with Toxoplasma gondii depends on the parasite genotype.Semantic proximity Read ↗

A genome-wide loss-of-function screen identifies <i>Toxoplasma gondii</i> genes that determine fitness in interferon gamma-activated murine macrophagesSemantic proximity Read ↗

Genetic basis for phenotypic differences between different Toxoplasma gondii type I strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.