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Article

Production of IL-12 by macrophages infected with Toxoplasma gondii depends on the parasite genotype.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2004

Robben Paul M, Mordue Dana G, Truscott Steven M, Takeda Kiyoshi, Akira Shizuo, Sibley L David

Abstract excerpt

Three clonal strain types (I, II, and III) of Toxoplasma gondii predominate worldwide. The outcome of infection in mice is highly dependent on the parasite genotype with type I strains being uniformly virulent, while types II and III are nonvirulent. Interactions with the innate immune response play a major role in determining the outcome of infection in the murine model. To identify key early differences in the...

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Share to Antigens, Differentiation
Share to Dose-Response Relationship, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mice, Inbred C3H

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Source

Identifiers

PMID: 15004172
DOI: 10.4049/jimmunol.172.6.3686

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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