Article
The role of ZmpC in the clinical manifestation of invasive pneumococcal disease.
International journal of medical microbiology : IJMM - 1 Nov 2014
Cremers Amelieke J H, Kokmeijer Ishana, Groh Laszlo, de Jonge Marien I, Ferwerda Gerben
Abstract excerpt
INTRODUCTION: The clinical severity and course of invasive pneumococcal disease (IPD) differs substantially between patients. Streptococcus pneumoniae harbors large genetic variability. Zinc metalloproteinase C (ZmpC), a secreted pneumococcal protein involved in neutrophil extravasation, inflammation and tissue remodeling, is present in a minority of IPD isolates. We investigated whether the presence of zmpC was...
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