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Could valproic acid be an effective anticancer agent? The evidence so far

14 Jul 2014

Abstract excerpt

Valproic acid is an inhibitor of class I histone deacetylases. Epigenetic therapies in cancer have been focus of a keen interest and histone deacetylase inhibitors, in particular, have been approved for certain types of hematologic malignancies. Valproic acid is an attractive candidate for cancer therapy due to its mechanism of action, its low cost and generally good clinical tolerability. In the following...

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PMID: 25017212
DOI: 10.1586/14737140.2014.940329

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