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The Epigenetic Modifier, Valproic Acid, Enhances Radiation Sensitivity

1 Jul 2006

Abstract excerpt

Valproic acid is an established therapeutic for a variety of seizure disorders and in certain cases for depression and anxiety. In addition, valproic acid has been shown to possess histone deacetylase inhibition activity and is currently being investigated as an anti-cancer agent, either alone or in combination with other conventional cancer therapies such as ionizing radiation. In this study, we investigated...

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PMID: 17965607
DOI: 10.4161/epi.1.3.2896

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