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Article

Are ALOX5AP gene SNPs a risk or protective factor for stroke?

Gene - 10 Sept 2014

Papapostolou Apostolis, Spengos Kostas, Fylaktou Irene, Poulou Myrto, Gountas Ilias, Kitsiou-Tzeli Sophia, Kanavakis Emmanuel, Tzetis Maria

Abstract excerpt

ALOX5AP (5-lipoxygenase) has been recognized as a susceptibility gene for stroke. Using a case-control design, the whole coding and adjoining intronic regions of ALOX5AP were sequenced to study the role of SNPs and their interplay with other risk factors in Greek patients with stroke. Patients (n=213) were classified by the Trial of Org 10172 in Acute Stroke Treatment (TOAST). Their mean age of was 58.9 ± 14.64,...

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Source

Identifiers

PMID: 25010723
DOI: 10.1016/j.gene.2014.07.007

Genes

CAD
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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