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Article

PPM1D is a prognostic marker and therapeutic target in colorectal cancer

6 Jun 2014

Abstract excerpt

Protein phosphatase, Mg2+/Mn2+ dependent, 1D (PPM1D) has been associated with carcinogenesis. The present study investigated PPM1D expression as a potential biomarker in colorectal cancer (CRC). PPM1D expression was assessed using immunohistochemistry in 368 patients with CRC. The correlation between PPM1D expression, clinicopathological features and prognosis was analyzed. PPM1D small interfering (si)RNA‑induced...

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Identifiers

PMID: 25009596
DOI: 10.3892/etm.2014.1762

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